Prolonged respiratory viral shedding in transplant patients |
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Authors: | CRA de Lima TB Mirandolli LC Carneiro C Tusset CM Romer HF Andreolla LF Baethgen AC Pasqualotto |
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Institution: | 1. Department of Basic Health Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), , Porto Alegre, Brazil;2. Molecular Biology Laboratory, Santa Casa de Misericordia de Porto Alegre, , Porto Alegre, Brazil |
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Abstract: | Respiratory viral infections are frequent causes of morbidity in transplant patients. We screened symptomatic adult transplant recipients for respiratory viruses in a cohort of patients attending a referral medical center in Brazil. The duration of viral shedding and the prevalence of viral codetections were also determined. During a 1‐year period (2011–2012), swabs were obtained from 50 patients. An in‐house polymerase chain reaction panel designed to detect 10 viruses was used. Viruses were identified in 19 (38%) patients, particularly parainfluenza III (32%) and the respiratory syncytial virus (20%); multiple viruses were identified in 26% of patients. Prolonged viral shedding was observed with 60% of individuals excreting viruses for >10 days. The clinical and epidemiologic relevance of prolonged viral shedding remains to be determined. |
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Keywords: | respiratory tract infection viruses PCR transplant infectious diseases |
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