颈椎自体和异体骨移植早期并发症的回顾比较研究

目的 研究异体骨移植对颈椎椎体融合术早期并发症发生率和术后留院时间的影响。方法 分析1997～2003年103例颈椎前路手术异体骨移植患者早期并发症发生率,与同期手术的145例自体骨移植患者比较。结果 异体骨移植患者手术时间短,术后留院时间短,感染性并发症发生率少于自体骨移植者。结论 异体骨移植风险小,医疗资源消耗少,适合临床应用。

Is allograft a procedure with high-risk in anterior cervical fusion

Objective The anterior cervical autograft or allograft interbody fusion had become an accepted fusion technique for treating patients with degenerative disorders of the cervical spine. In this retrospectve review, a comparison of allograft and autograft of bone was presented. Methods A retrospective review of 103 patients who had undergone allograft fusion and 145 patients with autograft fusion between 1997 and 2003, was conducted. Demographics, early complications and length of stay of patient were compared. Results Longer time on operation with the use of autograft (P<0.001) and significant increase in length of stay were observed after autograft (P<0.001). Complication of infections in autograft group was higher than allograft (P<0.05). Conclusions Both autograft and allograft were effective during fusion procedures. Allograft did not appear to be a high risk factor and could decrease medical cost thus could be used clinically for anterior cervical fusion.