| 老年高血压病人监测血清Ⅲ型前胶原的临床意义 |
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| 引用本文： | 刘洪霞,李晨新,李健,刘洪爱,王克平,江新泉. 老年高血压病人监测血清Ⅲ型前胶原的临床意义[J]. 中国慢性病预防与控制, 2001, 9(2): 58-59 |
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| 作者姓名： | 刘洪霞 李晨新 李健 刘洪爱 王克平 江新泉 |
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| 作者单位： | 1. 泰山慢性病医院,
2. 山东省省立医院, |
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| 摘 要： | 目的研究老年高血压病人血清Ⅲ型前胶原(PCⅢ)的浓度变化及临床意义。方法应用放免法测定33例Ⅰ、Ⅱ期老年高血压患者血清PCⅢ的含量，以20例血压正常的同龄健康人作对照；同时对病人行心脏彩色多普勒检查，测定左室重量(LVM)及二尖瓣口舒张早期、舒张晚期最大血流速度(V
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| 关 键 词： | 高血压 Ⅲ型前胶原 心肌纤维化 心功能 |
| 文章编号： | 1004-6194(2001)02-0058-02 |
| 修稿时间： | 2000-02-24 |
The Clinical Significanceof Monitoring Serum Procollagen Type |
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| LIU Hong xia,et al,Taishan Chronic Disease Hospital,Shangdong ,China. The Clinical Significanceof Monitoring Serum Procollagen Type[J]. Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases, 2001, 9(2): 58-59 |
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| Authors: | LIU Hong xia et al Taishan Chronic Disease Hospital Shangdong China |
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| Affiliation: | LIU Hong xia,et al,Taishan Chronic Disease Hospital,Shangdong 271000,China |
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| Abstract: | Objective To study the changes in concentration of serum procollagen type Ⅲ (PCⅢ) and the correlations between the PCⅢ and cardiac function parameters(VE/VA),left ventricular mass(LVM) in aged essential hypertensive patients.Methods The concentration of PCⅢ was measured by radioimmunoassay in 33 aged essential hypertensive patients and 20 normotensive subjects.At same time,two-dimensional M-mode Doppler ultrasound examination was made to determine patient's LVM,maximal early transmittal flow velocity(VE) and maximal late transmittal flow velocity(VA).Results The concentration of serum PCⅢ increased in aged essential hypertensives than that in normotensives (P＜0.001).And in aged essential hypertensives,an inverse correlation was found between PCⅢ and VE/VA(P＜0.05);but there is no relationship between PCⅢ and LVM(P＞0.05).Conclusions PCⅢ involved in the occurrence and development of the essential hypertension,which made myocardium fibrosis and affected cardiac diastolic function. |
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