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防治心肌缺血/再灌注损伤心肌mPTP开放情况的研究进展
引用本文:王超,刘昭,张佳丽,常小荣,严洁,刘密.防治心肌缺血/再灌注损伤心肌mPTP开放情况的研究进展[J].辽宁中医杂志,2013(12):2615-2617.
作者姓名:王超  刘昭  张佳丽  常小荣  严洁  刘密
作者单位:湖南中医药大学针灸推拿学院,湖南长沙410007
基金项目:国家自然科学基金课题资助(81072868;81102661)
摘    要:本文对最近5-8年来国内外防治心肌缺血/再灌注损伤(MIRI)的机制研究进行了总结和归纳,试图使在防治心肌缺血/再灌注损伤中调控线粒体通透性转换孔(mPTP)开放机制的研究方面有所发现,为防治心肌缺血再灌注损伤提供更多更有力的理论依据。

关 键 词:心肌缺血/再灌注损伤  线粒体通透性转换孔  mPTP

Progress of Studies on Prevention of Myocardial Ischemia/ Reperfusion Injury in Myocardial mPTP Open
WANG Chao,LIU Zhao,ZHANG Jiali,CHANG Xiaorong,YAN Jie,LIU Mi.Progress of Studies on Prevention of Myocardial Ischemia/ Reperfusion Injury in Myocardial mPTP Open[J].Liaoning Journal of Traditional Chinese Medicine,2013(12):2615-2617.
Authors:WANG Chao  LIU Zhao  ZHANG Jiali  CHANG Xiaorong  YAN Jie  LIU Mi
Institution:(Acupuncture and Massage College of Hunan University of Chinese Medicine, Changsha 410007 ,Hunan, China)
Abstract:In this paper, we reviewed and summarized the research .of domestic and international mechanisms for the preven tion of myocardial isehemia - reperfusion injury in the last 5 - 8 years, trying to discovery the prevention of myocardial ischemia - reperfusion injury in the regulation of the mitochondrial permeability transition pore (mPTP)open meehanism studies and provi ding more powerful theoretical basis for the prevention and treatment of myocardial ischemia - reperfusion injury.
Keywords:myocardial ischemia/reperfusion injury  mitochondriat permeability transition pore  mPTP
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