自拟滋肾调更汤治疗围绝经期综合征36例

目的:观察自拟滋肾调更汤治疗围绝经期综合征的疗效。方法:将72例患者随机分为自拟滋肾调更汤组(治疗组)36例和替勃龙片组(对照组)36例。两组临床观察均以2个月为1个疗程,共观察1个疗程,以临床疗效及治疗前后Kupperam Index症状评分(下称KI评分)改善作为观察指标。结果:治疗前后两组KI评分自身比较,均见P<0.01,差异有统计学意义,治疗后组间比较P>0.05,无显著性差异;治疗后两组围绝经期症状均有不同程度改善,但治疗组对很多症状及症状改善程度明显(P<0.05,P<0.01),治疗后两组组间比较,差异无显著性(P>0.05)。结论:自拟滋肾调更汤治疗围绝经期综合征疗效显著。

Clinical Observation of Modified Zishen Tiaogeng Decoction on Treating 36 Cases with Perimenopausal Syndrome

Objective：To observe the eurative effect of modified Zishen Tiaogeng Decoction on treating perimenopausal syndrome. Methods ：72 eases were randomly divided into two groups, and treated with modified Zishen Tiaogeng Decoetion （ treatment group） or Tibolone （control group） for two months as a course. Then, before and after treatment, menopausal syndrome was observed using the clinical effects and Kupperman Index（KI） as the indexes. Results：Before and after treatment, KI had statistical difference （P 〈0. 01 ） in two groups. And there was no significant difference between them after the treating （P 〉 0. 05 ）. The symptoms of perimenopausal syndrome were both improved in two groups. But the treatment group had more changes than the con- trol group. Conclusion：Modified Zishen Tiaogeng Decoction was effective on treating perimenopausal syndrome.