姜黄素对大鼠调节血脂及抗氧化作用的研究

为研究姜黄素的降脂作用抗氧化作用，将高脂血症模型大鼠根据血总胆固醇水平随机分为４组：基础饲料对照组喂基础饲料＋姜黄素组喂加入姜黄素５ｇ／ｋｇ的基础饲料；高脂饲料对照组喂高脂饲料；高脂饲料＋姜黄素组喂加入姜黄素ｇ／ｋｇ的高脂饲料。再喂养４周，测定血脂及抗氧化指标。结果显示姜黄素能降低高脂模型大鼠血中总胆固醇、甘油三酯水平，提高载脂蛋白Ａ水平，并降低血及肝中过氧化脂质，直匀浆总抗氧化能力和ＳＯＤ活性、

Regulation effect of curcumin on blood lipids and antioxidation in hyperlipoidemia rats

The regulation effects of curcumin on lowering blood lipids and antioxidation were studied in the hyperlipoidem ia model Wistar rats fed with high fat diet for 4weeks.The hyperlipoidemia m odel rats were then separated into four groups:normal diet group,norm al diet curcumin(5 g/ kg) group,high- fat diet group and high- fat diet curcum in group.The rats were fed with experimental diets for another 4 weeks respectively.The results indicated that curcumin decreased the serum levels of cholesterol and triglyceride and increased the serum level of apolipoprotein A.Curcumin decreased TBA value and improved total antioxidation capability.The activities of SOD and GSH- PX in liver were enhanced.After taking norm al diet for four weeks,the blood fat and cholesterol levels of the hyperlipoidemia rats recovered.Butin the normal diet curcumin group,the same results could be found in two weeks.