基于文献的中国军队腺病毒感染流行特征分析

目的 分析近年中国军队腺病毒感染的流行病学特征,探讨流行规律,为处置军队暴发疫情提供理论依据.方法 从中国知网、万方和维普数据库收集1999年6月—2019年8月公开发表的中国军队腺病毒流行及暴发疫情文献,对疫情的病毒分型、暴发时间(包括年份和月份)、地区分布、人群结构和临床特征进行统计学分析.结果 共检索到中国军队腺...

Epidemiological characteristics of Human adenovirus infection in Chinese army: literature-based analysis

Objective To analyze the epidemiological characteristics of Human adenovirus(HAdV) infection in Chinese army in recent years, and explore the epidemic trend, so as to provide theoretical basis for the disposal of military epidemic outbreaks. Methods Literatures on epidemic outbreak of HAdV in Chinese army published from June 1999 to August 2019 were collected from China National Knowledge Infrastructure (CNKI), Wanfang Database and VIP Database. Virus typing, outbreak time (including year and month), regional distribution, population structure and clinical characteristics were analyzed statistically. Results A total of 44 available literatures on HAdV epidemic outbreaks in Chinese army were retrieved, including 46 events of epidemic outbreaks involving 8 710 cases of infection. The types of HAdV causing the epidemic included type 3 (1 event), type 5 (2 events), type 7 (19 events), type 11 (1 event), type 55 (16 events) and unclassified type (7 events); type 7 and type 55 accounted for 41.3% (19 events) and 34.8% (16 events) respectively; the number of infection accounted for 49.5% (4 312 cases) and 35. 9% (3 129 cases) respectively. The outbreaks in January, February and December accounted for 76.1% (35 events) of the total outbreaks, and the number of infection cases accounted for 91.8% (7 999 cases); the main population with infection were recruits or cadets, accounting for 89.2% (2 504/2 807) of the total population; the main clinical manifestations were fever, cough, sore throat and pharyngeal congestion; type 7 and type 55 HAdV infection were the most common, which was prone to be severe. Conclusion Type 7 and type 55 are the most common types of HAdV infection in Chinese army, during training of recruits or cadets in winter and spring, prevention and control of HAdV infection should be strengthened to prevent the outbreak of HAdV infection.