| 同种异体大鼠肾移植实验动物模型的建立 |
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| 引用本文： | 潘浩,温端改,欧阳骏,平季根,刘忠国,王祖峰,孙鹤云. 同种异体大鼠肾移植实验动物模型的建立[J]. 苏州大学学报(自然科学版), 2007, 27(3): 354-355,358 |
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| 作者姓名： | 潘浩 温端改 欧阳骏 平季根 刘忠国 王祖峰 孙鹤云 |
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| 作者单位： | 苏州大学附属第一医院泌尿外科,江苏苏州215006 |
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| 摘 要： | 目的建立大鼠异体肾移植模型,为开展器官移植的实验研究提供依据。方法使用SD大鼠分别作为供者和受者,采用原位低温灌洗,移植肾放置左侧,血管直接吻合,输尿管带膀胱瓣与膀胱吻合。结果建立了比较稳定的大鼠同种异体肾移植模型。手术成功率为90%。结论此模型较容易掌握,可以在条件比较简单的实验室开展,除常规显微外科器械外不需要特殊的器械或设备。
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| 关 键 词： | 肾移植 动物模型 大鼠 |
| 文章编号： | 1673-0399（2007）03-0354-02 |
| 修稿时间： | 2006-02-21 |
A Rat Model of Kidney Transplantation |
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| PAN Hao,WEN Duan-gai,OU Yang-jun,PING Ji-gen,LIU Zhong-guo,WANG Zu-feng,SUN He-yun. A Rat Model of Kidney Transplantation[J]. Suzhou University Journal of Medical Science, 2007, 27(3): 354-355,358 |
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| Authors: | PAN Hao WEN Duan-gai OU Yang-jun PING Ji-gen LIU Zhong-guo WANG Zu-feng SUN He-yun |
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| Affiliation: | Dept of Urology, the First Hospital Affiliated to Suzhou University,Jiangsu Suzhou 215000, China |
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| Abstract: | Objective To expand laboratory investgation of organ transplantation and prepare a model of kidney transplantation.Methods SD rats were served as donors and recipients.Hypothermia infusion was conducted and prepared at prime position.Donor kidney was grafted at the left side.Direct vascular anastomoses and connecting the donor ureter with ureterocystic flap to the recipient's bladder were conducted.Results We have established a stable model of rat kidney transplantation.Our operation success rate reached 90% or so.Conclusion This model of kidney transplantation is feasible regardless of experimental conditions.The another advantage of it over others is in fact that there is no special equipment to be needed except microsurgical instrument. |
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| Keywords: | kidney transplantation animal model rats |
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