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治疗痛风新药非布司他的临床研究进展
引用本文:张源潮,户中丹,杨兆文,王威严. 治疗痛风新药非布司他的临床研究进展[J]. 世界临床药物, 2014, 0(9): 519-522
作者姓名:张源潮  户中丹  杨兆文  王威严
作者单位:山东大学附属省立医院风湿免疫科,济南250021
摘    要:痛风是成人常见的炎症性关节炎类型之一。选择性黄嘌呤氧化酶抑制剂非布司他是一种高尿酸血症和痛风治疗新药。本文综述其药动学、作用机制及临床研究。

关 键 词:非布司他  痛风  降尿酸药物

Advance in clinical research of febuxostat in the treatment of gout
ZHANG Yuan-chao,HU Zhong-dan,YANG Zhao-wen,WANG Wei-yan. Advance in clinical research of febuxostat in the treatment of gout[J]. WORLD CLINICAL DRUGS, 2014, 0(9): 519-522
Authors:ZHANG Yuan-chao  HU Zhong-dan  YANG Zhao-wen  WANG Wei-yan
Affiliation:(Department of Rheumatology and Immunology, Shandong Provincial Hospital, Shandong University, Ji 'nan 250021, China)
Abstract:Gout is one of the most common inflammatory arthritis in adults. Febuxostat is a new drug for the treatment of hyperuricemia and gout through inhibiting xanthine oxidase. This review summarizes its pharmacokinetic, pharmacological effects and clinical studies.
Keywords:febuxostat  gout  hypouricemic drug
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