两类功能性便秘患者行生物反馈治疗的疗效及随访比较

目的比较生物反馈治疗对两类功能性便秘（FC）的临床疗效及随访效果。方法选择2010年1月至2013年1月收治的72例FC患者,其中慢传输型便秘（STC）患者37例、出口梗阻型便秘（OOC）患者35例。所有患者均行生物反馈治疗,比较患者肛管静息压和肛管最大收缩压,并进行为期半年的随访。结果所有患者均完成2周生物反馈治疗,治疗后OOC组的肛管静息压与入院时同组和治疗后STC组相比,差异均无统计学意义;但治疗后OOC组肛管最大收缩压（146.73±24.51）mmHg明显高于入院时同组（112.51±22.5）mmHg及治疗后STC组（108.35±21.29）mmHg,P〈0.05。所有患者均随访半年。随访后OOC组的汉密尔顿焦虑量表（HAMA）评分（8.25±2.27）显著低于入院时同组（11.01±3.14）及随访后STC组（11.43±3.71）,P〈0.05。随访后OCC组的疾病不确定感量表（MUIS）评分（36.45±7.43）显著低于入院时同组（50.45±12.48）及随访后STC组（44.42±9.67）,P〈0.05。但随访后OCC组的Zung抑郁自评量表（SDS）评分与入院时同组及随访后STC组相比差异均无统计学意义。两组患者总体有效率相比,差异无统计学意义;但OOC组患者治愈率（48.57%）明显高于STC组（29.73%）,P〈0.05。结论生物反馈能有效治疗FC,对OOC的疗效更好。

Comparison of biofeedback therapy and follow-up of patients with two functional constipations

Objective This paper intends to compare the biofeedback therapy in slow transit constipation（ STC） and outlet obstruction constipation（ OOC）. Methods 72 patients with functional constipation from Jan 2010 to Jan 2013 were divided into2 groups via colonic transit index,of which 37 patients were assigned to the STC group,while 35 patients to the OOC group. All patients underwent biofeedback therapy. The anal resting pressure and maximum anal systolic pressure of the patients were compared,and a six-month follow-up were conducted. Results All patients were treated with biological feedback therapy for two weeks. The anal resting pressure of the OOC group after treatment were compared with the one before treatment in the same group and the one after treatment in the STC group,but no statistical significant difference were observed. However the maximal anal systolic pressure after treatment in the OOC group（ 146. 73 ± 24. 51） mmHg was significantly higher than the one before treatment in the OOC group（112. 51 ± 22. 5） mmHg and the one after treatment in the STC group（108. 35 ± 21. 29） mmHg,P〈0. 05. All patients were followed up for half a year. After being followed up,the HAMA score in the OOC group（8. 25 ± 2.27） was significantly lower than the one in the same group before treatment（11. 01 ± 3. 14） and the one in the STC group after being followed up（11. 43 ± 3. 71）,P〈 0. 05. After being followed up,the MUIS score in the OOC group（ 36. 45 ± 7. 43）was significantly lower than the one in the same group before treatment（ 50. 45 ± 12. 48） and the one in the STC group after being followed up（44. 42 ± 9. 67）,P〈0. 05. However,no statistical significance was observed among the Zung SDS scores of the OOC group after being followed up,the one in the same group before treatment,and the one in the STC group after being followed up. The general treatment efficiency of the patients in the two groups were compared. No statistical significance was observed,but the cure rate o