Oral traumatic granuloma: Characterization of the cellular infiltrate |
| |
| Affiliation: | 1. Division of Oral Pathology, Department of Stomatology, School of Dentistry, University of California, San Francisco, USA;2. Department of Pathology, Henry Ford Hospital Detroit, USA;1. Centre hospitalier universitaire de Treichville, service d’oncologie, Abidjan, Côte d’Ivoire;2. Institut Pasteur, unité de sérologies bactériennes et virales, Mermoz, Abidjan, Côte d’Ivoire;3. Université médicale Félix Houphouët-Boigny, département de microbiologie, 01 BPV 166, Abidjan, Côte d’Ivoire;4. Centre hospitalier universitaire de Cocody, service d’hépatogastroentérologie, Mermoz, Abidjan, Côte d’Ivoire;5. Centre hospitalier universitaire de Yopougon, service de médecine et hépatogastroentérologie, Abidjan, Côte d’Ivoire;6. CHU de Treichville, service de médecine interne, Abidjan, Côte d’Ivoire;7. Hôpital militaire d’Abidjan, service de médecine interne, Abidjan, Côte d’Ivoire;8. Centre hospitalier universitaire de Treichville, registre des cancers, Abidjan, Côte d’Ivoire;9. Unité de Formation et de Recherche (UFR) Sciences médicales Abidjan, département d’immunologie -hemato-cancérologie, 01 BPV 166, Abidjan, Côte d’Ivoire;10. Programme national de lutte contre le cancer (PNLCa), Abidjan, Côte d’Ivoire;11. Institut Pasteur, Inserm U993, unité « organisation nucléaire et oncogenèse », 75000 Paris, France;1. Professor and Chairman, Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Tokyo, Japan;2. Assistant Professor and Chairman, Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Tokyo, Japan;3. Director, Department of Oral and Maxillofacial Surgery, Mita Hospital, International Health and Welfare University, Tokyo, Japan;4. Professor and Chairman, Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine, Hyogo, Japan;6. President, Japanese Society of Dentistry for Medically Compromised Patient and Dokkyo University, Tochigi, Japan;5. President, Japanese Society of Oral and Maxillofacial Surgeons and School of Dentistry, Aichi-Gakuin University, Aichi, Japan;1. Service de chirurgie maxillo-faciale et stomatologie, CHU d’Angers, 4, rue Larrey, 49933 Angers cedex, France;2. Service d’ORL et chirurgie cervico-faciale, CHU d’Angers, 4, rue Larrey, 49933 Angers cedex, France;1. P.G. & Research Department of Chemistry, C.P.A. College, Bodinayakanur-625 513, Tamil Nadu, India;2. Directorate of Distance Education, Madurai Kamaraj University, Palkalai Nagar, Madurai-625 021, Tamil Nadu, India;3. Mother Teresa Women’s University, Kodaikanal-624 102, Tamil Nadu, India;4. PG & Research Department of Chemistry, Thiagarajar College, Madurai 625 009, Tamil Nadu, India;1. Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322, United States;2. Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803, United States;1. Department of Oral Diagnosis and Medicine, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan;2. Department of Gerodontology, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan |
| |
| Abstract: | Oral traumatic granulomas are reactive mucosal lesions that are characterized by an intense mononuclear infiltrate (usually with eosinophils) that may mimic neoplasia. These pseudoneoplastic infiltrates were evaluated with the use of lineage-associated antibodies (CD3, OPD4, L26, KP1, XIIIa. S-100, HPCA-1, HHF-35). We determined that the large distinguishing mononuclear cells were either CD68-positive macrophages or factor XIIIa-positive dendrocytes (the oral counterparts to dermal dendrocytes). S-100-positive connective tissue cells occasionally contributed to this infiltrate. Also abundant in the infiltrate were smaller CD3-positive T-lymphocytes. Double-staining confirmed that there were separate populations of CD68-positive macrophages and Xllla-positive dendrocytes. Because some XIIIa dendrocytes coexpressed CD68, phagocytosis may be one of the functions of dendrocytes. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
