Effectiveness of dupilumab in pediatric patients with a nummular phenotype of atopic dermatitis |
| |
Authors: | Eun Jae Kim BA Madeline Hlobik BA Tina Ho MD PhD |
| |
Institution: | 1. Harvard Medical School, Boston, Massachusetts, USA;2. Dermatology Section, Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, USA |
| |
Abstract: | The nummular phenotype of atopic dermatitis is clinically characterized by pruritic, coin-shaped plaques that are frequently recalcitrant to treatment. In this study, a retrospective chart review was conducted to evaluate the effectiveness and safety of dupilumab in children with nummular lesions of dermatitis. Twelve out of 14 patients demonstrated significant clinical improvement at a median time of 2.5 months (interquartile range, 1–4) after dupilumab initiation. A single case of paradoxical psoriasiform eruption was the only side effect reported in our cohort. |
| |
Keywords: | atopic dermatitis dupilumab nummular dermatitis |
|
|