胃粘膜相关淋巴组织淋巴瘤的外科治疗

目的 探讨胃粘膜相关淋巴组织淋巴瘤外科治疗经验。方法 回顾性复习1984－1996年手术治疗的69例胃粘膜相关淋巴组织淋巴瘤患者的临床资料。结果 69例中I期26例Ⅱ期21例、Ⅲ期13例、Ⅳ期9例，全组病例均经手术及理证实。病变完全切除者61例，部分切除者4例，未切除者4例。单纯手术切除者5例，手术加放疗25例，手术加化疗19例，手术加放疗、化疗20例。全组总的5年生存率71％（49／69），10年生存率31．9％（22／69）。结论 临床分期及治疗方法是影响预后的主要因素，年龄与性别与预后无关。外科手术在胃粘膜相关淋巴组织淋巴瘤治疗中是重要治疗手段。

Surgical treatment ofgastric mucosa-associated lymphoid tissue lymphoma

Objective　To study the experience in surgical treatment of gastric mucosa-associated lymphoid tissue lymphoma (GMALTL). Methods　The clinical data of 69 cases of GMALTL from 1984 to 1996 were reviewed. Results　In this series, there were 26 cases in stage Ⅰ, 21 in stageⅡ, 13 in stage Ⅲ and 9 in stage Ⅳ. Diagnosis was proved by both surgery and pathology in all the cases. 61 cases underwent curative resection, 4 incomplete resect and 4 unresectable. Among them, 5 cases were treated by surgery only, surgery plus postoperative radiotherapy used in 25 cases, 19 received surgery plus postoperative chemotherapy, and 20 cases received surgery plus chemotherapy and radiotherapy. 57 cases (82.6%) were following up for 1 to 12 years.The 5,10-year survival rate was 71%(49/69)and 31.9%(22/69) respectively. Conclusions　Clinical stage and therapeutic modality adopted do the major prognostic foctors ,while age and gender do not count much to the recovery. Surgery remains to be the most important treatment model.