健康人不同中医体质者血清甲状腺激素水平的比较研究

目的探讨健康人不同中医体质者甲状腺的功能状况。方法2012年7月和2013年7月，以中国中医科学院广安门医院体检中心的体检者为样本库，测定9种体质健康人的血清三碘甲状腺原氨酸（T3）、甲状腺素（T4）、游离T3（FT3）、游离T4（FT4）及促甲状腺激素（TSH）的水平。结果9种体质健康人T3、T4、FT3、FT4、TSH水平存在一定的差异，其中平和质、湿热质FT3与阳虚质比较，差异均有统计学意义（P〈0．05）；阳虚质、特禀质FT3与湿热质比较，差异均有统计学意义（P〈0．05）。结论湿热质与平和质比较，其基础代谢较快；气虚质、阳虚质可能与下丘脑-垂体-甲状腺轴功能减退有关；痰湿质可能与下丘脑-垂体-甲状腺轴功能亢进有关。

Comparison of serum levels of thyroid hormone in healthy participants with different TCM constitution

Objective To explore the functional status of thyroid in healthy participants with different TCM constitution. Methods From July of 2012 to January of 2013, the health examination participants in Medical Examination Center of China Academy of Chinese Medical Sciences were selected as samples to measure triiodothyronine （T3）, thyroxine （T4）, free T3 （Fq3）, free T4 （FT4） and thyroid stimulating hormone （TSH） in 9 kinds of constitutions. Results Among 9 kinds of constitutions, there were some differences on levels of T3, T4, FT3, Fl＇4 and TSH; compared with yang-deficieney constitution, T3 in the moderate constitution and damp-hot constitution were significantly different （P 〈 0. 05） ; compared with damp-hot constitution, special constitution and yang-deficiency constitution were significantly different （P 〈 0.05）. Conclusion The damp-hot constitution has faster basic metabolism than moderate constitution; qi-deficiency constitution and yang-deficiency constitution may be related with recession of hypothalamic-pituitary-thyroid axis ; phlegm-damp constitution is related with hyperfunction of hypothalamic-pituitary-thyroid axis.