| HPLC法测定通天口服液中马兜铃酸A的含量 |
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| 引用本文： | 彭涛,肖礼娥,余佳文,秦少容.HPLC法测定通天口服液中马兜铃酸A的含量[J].中国中医药咨讯,2012,4(5):152-152. |
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| 作者姓名： | 彭涛 肖礼娥 余佳文 秦少容 |
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| 作者单位： | 太极集团重庆涪陵制药厂有限公司,重庆,408000 |
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| 摘 要： | 目的：建立通天口服液中马兜铃酸A 的含量测定法.方法：色谱柱为DiamonsilTM C18（5μm,4.6×250mm）;流动相为0.02%十二烷基硫酸钠溶液- 乙腈（50：50）,用磷酸调pH 值为2.0;检测波长为390nm.结果：在0.817-8.168ng 进样范围内,马兜铃酸A 的峰面积与进样量线性关系良好（r=0.99973）.结论：该法可用于通天口服液中马兜铃酸A 的含量检测.
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| 关 键 词： | 通天口服液 马兜铃酸A HPLC法 |
Determination of Aristolochic Acid in Tongtian Oral Liquor by HPLC |
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| PENG Tao,Xiao Li-e,YU Jiawen,QIN Shaorong.Determination of Aristolochic Acid in Tongtian Oral Liquor by HPLC[J].Journal of China Traditional Chinese Medicine Information,2012,4(5):152-152. |
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| Authors: | PENG Tao Xiao Li-e YU Jiawen QIN Shaorong |
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| Institution: | (Taiji chongqing ruling pharmaceutical group Co., LTD, chongqing, 408000) |
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| Abstract: | Objective：To establish amethod for the determination of aristolechic acid in Tongtian Oral Liquor by HPLC.Methods： DiamonsilTM C18 （5μm,4.6×250mm））, mobile phase composed of acetonitrile- 0.02% sodium dodecyl sulfate （50 ： 50）, Use phosphoric acid to adjust the pH value to 2.0;detection wave-length at 390nm.Resuhs：The calibration curvewas linear at the range of 0.817-8.168ng （r=-0. 999 73）.Conclusion：Themethod can be used for determination of aristolochic acidA in Tongtian Oral Liquor. |
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| Keywords: | Tongtian Oral Liquor aristolochic acidA HPLC method |
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