| 氧化应激与胎膜早破的相关性研究 |
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| 引用本文： | 马秀菊,肖文霞. 氧化应激与胎膜早破的相关性研究[J]. 中国优生与遗传杂志, 2006, 14(1): 69-70 |
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| 作者姓名： | 马秀菊 肖文霞 |
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| 作者单位： | 河北医科大学第二医院妇产科,河北石家庄,050000 |
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| 摘 要： | 目的通过对胎膜早破孕妇蜕膜和血清中氧化应激指标—超氧化物歧化酶(SOD)、丙二醛(MDA)及维生素E(VE)的测定,探讨氧化应激与胎膜早破的关系。方法用化学比色法对30例胎膜早破孕妇和30例正常孕足月妇女蜕膜和血清中SOD、MDA及VE进行测定。结果与正常孕足月妇女相比,胎膜早破孕妇蜕膜和血清中MDA水平都升高(P<0.05),SOD、VE水平却都下降(P<0.05,P<0.05)。结论氧化应激与胎膜早破具有相关性。
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| 关 键 词： | 氧化应激 胎膜早破 超氧化物歧化酶 丙二醛 维生素E |
| 文章编号： | 1006-9534(2006)01-0069-02 |
| 修稿时间： | 2005-05-21 |
The study of relationship between oxidative stress and premature rupture of membranes |
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| MA Xiu-ju,XIAO Wen-xia. The study of relationship between oxidative stress and premature rupture of membranes[J]. Chinese Journal of Birth Health & Heredity, 2006, 14(1): 69-70 |
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| Authors: | MA Xiu-ju XIAO Wen-xia |
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| Abstract: | Objective: To determine the levels of SOD,MDA and VE in decidua and maternal serum of patients with premature rupture of membranes to clarify relationship between oxidative stress and premature rupture of membranes.Methods: The levels of SOD,MDA and VE in decidua and maternal serum were measured in 30 patients with premature rupture of membranes and 30 term-pregnant women by chemocolorimetry.Results: The levels of MDA in decidua and maternal serum of patients with premature rupture of membranes were significantly higher than those of term-pregnant women(P<0.05),while the levels of SOD and VE were significantly decreased(P<0.05,P<0.05).Conclusion: Oxidative stress is associated with premature rupture of membranes. |
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| Keywords: | Oxidative stress Premature rupture of membranes Superoxide dismutase Malondialdehyde Vitamin E |
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