癫痫的X刀治疗

目的 探讨X刀治疗继发性癫痫(SEp)和原发性颞叶癫痫(ITLEp)的方法。方法 使用24hEEG、CT、MRI对继发性癫痫灶定位，应用X刀损毁致痫灶治疗SEp40例；毁损剂量20～30Gy。应用X刀毁损杏仁核治疗ITLEp病人30例；毁损剂量140Gy；准直仪7～10mm；采用140Gy一次和分两次毁损治疗(每次间隔24h)。结果 40例SEp病人和30例ITLEp病人X刀治疗后4～24个月随访：50例病人癫痫发作完全停止(SEp32例，ITLEp18例)；20例病人发作减少50％以上；无并发症发生。结论 应用X刀毁损SEp致痫灶及杏仁核，可安全有效地治疗SEp和ITLEp。

X knife treatment of epilepsy

Objective To investigate the curative effect of X knife treatment method for secondary epilepsy (SEp) and idiopathic temporal lobe epilepsy (ITLEp). Methods The 24-hour EEG,CT,MRI were used for locating the epileptogenic lesion of SEp.Forty patients of SEp were treated to destroy epileptogenic lesion by X knife with dose,20-30 Gy.Thirty patients of ITLEp were treated with X knife for amygdalectomy at 140 Gy and collimator 7-10 mm.The 140 Gy were given either by single full dose or 2-time fractionated treatment (Q.24.h). Results By 4-24 month follow-up of all these patients it was showed that seizures were alleviated completly in 50 patients (SEp 32 cases,ITLEp 18 cases),alleviated over 50% in 20 patients (SEp 8 cases,ITLEp 12 cases).No complications were observed. Conclusion X knife treatment of SEp is a useful and safe method to destroy epileptogenic lesion in patients with SEp and to perform amygdalectomy in patients with ITLEp.This methods is thus proved to be effective for such patients. ;