维生素A、锌、铜、钙对眼组织及视力的影响

本实验分别对动物和人群进行了维生素Ａ、锌、铜、钙与眼组织及视力关系的研究。动物实验主要观察维生素Ａ和锌对眼组织的影响。动物为封闭群Ｗｉｓｔａｒ健康大鼠，平均体重７４±１７ｇ，随机分为四组，实验期２５天，主要观察的指标为血清、肝脏和眼球中的维生素Ａ含量、血清锌含量以及眼球组织变化。结果表明，在维生素Ａ缺乏的情况下，摄入低锌时血清、肝脏和眼球的维生素Ａ含量明显低于摄入高锌者；当维生素Ａ供给充足时，低锌组与高锌组血清及各组织中的维生素Ａ含量无明显差别。提示，锌对眼球维生素Ａ含量的影响与维生素Ａ的水平及摄入量有关。人群实验主要观察了血清维生素Ａ、锌、铜、钙对视力的影响。筛选７２名一眼或双眼裸眼视力小于１．２的学生作为实验组，２３名双眼裸视力均在１．５以上者作为对照组。经检测，实验组血清锌、钙明显低于对照组，而铜、维生素Ａ含量在两组间无明显差别，说明体内锌、钙降低与近视有一定关系，而铜、维生素Ａ在本实验中未发现与近视有明显相关。

EFFECTS OF VITAMIN A,ZINC,COPPER AND CALCIUM ON OCULAR TISSUES AND SIGHT

he effects of vitanlin A,zinc,copper and calcium on eves were inves-tigated in rats and in adolescents.Thirty-six weanling Wistar rats lvere ran-domly divided into 4 grcups: vitamin A deficient combining lew zinc(A),vitamin A sufficient combining low zinc(B),vitamin A deficient combininghigh zinc(C),vitamin A sufficient combining high zinc(D).It was foundafter 25 days the vitamin A level in serum,liver and eye in group A weresignificantly lower than that of group C,but no difference between group Band group D,showing the influence of zinc on vitamin A in the eye wasrelated to the supplementary level of vitamin A,For the human subjects,the serum zinc and calcium levels in the myopia were significantly lowerthan those of the normal.There was no difference in the serum vitamin Aand copper levels between them. The results demonstrated that zinc or cal-cium deficiency was associated with myopia,but vitamin A or copper wasnot related.