自体肝移植治疗肝泡型包虫病经济负担研究

目的 针对终末期肝泡型包虫病（HAE）患者实施自体肝移植（ALT）治疗，探索其疾病经济负担及其影响因素。方法 收集2010年8月-2017年2月在新疆某三甲教学医院住院并行ALT术治疗的51例HAE患者的临床资料及各项费用数据，计算患者直接经济负担和间接经济负担，并对其影响因素进行单因素分析。结果 51例ALT术治疗的HAE患者经济负担为447 128.89元；其中直接经济负担257 943.45元（直接医疗费用为257 292.09元、直接非医疗费用为651.36元），占57.54%；间接经济负担189 834.06元，占42.46%。住院天数、年龄和职业等是影响患者住院费用的重要因素。结论 ALT术是一种有效解决终末期HAE的创新外科治疗方法，其疾病直接经济负担占的比重较高。通过以预防为主的同时针对接受ALT术的HAE患者加强医疗保障力度和提高救助标准等措施减轻患者的经济负担。

Economic burden of hepatic alveolar echinococcosis patients with autologous liver transplantation

Objective To investigate the disease burden and its impact factors in hepatic alveolar echinococcosis (HAE) patients with autologous liver transplantation (ALT).Methods Data on basic clinical and all relative costs were collected among 51 patients receiving ALT surgery for HAE treatment in a tertiary teaching hospital in Xinjiang Uygur Autonomous Region during August 2010 to February 2017.Both direct and indirect economic burden were calculated;then influencing factors of the disease burden were analyzed using univariate logistic regression.Results The average total economic burden for the HAE patients with ALT was 447 128.89 RMB Yuan,including direct economic burden (257 943.45 Yuan,57.54% of the total cost) and indirect economic burden (189 834.06 Yuan,42.46%).Days of hospitalization,age,and occupation are influencing factors of direct economic burden for the HAE patients.Conclusion The results of this study indicated that the direct cost accounts a major part of the disease burden for HAE patients with ALT,suggesting that the economic burden of the patients needs to be alleviated through improving medical security and financial supports.