The radiology of fibrolamellar hepatoma |
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| Authors: | A Adam R N Gibson O Soreide A P Hemingway D H Carr L H Blumgart D J Allison |
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| Institution: | 1. Department of Diagnostic Radiology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK;1. Flow Measurement and Fluid Mechanics Research Centre, Coventry University, Priory Street, Coventry CV1 5FB, UK;2. School of Energy, Construction and Environment, Built & Natural Environment Research Centre, Coventry University, Coventry CV1 5FB, UK;1. Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy;2. Department of Radiology, Erasmus Medical Center University, Rotterdam, the Netherlands;3. Department of Radiology, Montréal Heart Institute, Universitè de Montréal, Montreal, Quebec, Canada;1. Université Claude-Bernard Lyon 1, institut de cancérologie des hospices civils de Lyon, HCL, CITOHL, UR 3738 CICLY, Lyon, France;2. Hôpital Saint-Éloi, CNRS UMR 5535, département d’oncologie médicale, 80, avenue Augustin Fliche, 34295 Montpellier, France;3. Institut régional du cancer de Montpellier (ICM), unité d’oncologie médicale, Val d’Aurelle, 208, avenue des Apothicaires, 34298 Montpellier cedex 5, France;4. Hôpital Lyon Sud, hospices civils de Lyon, service de chirurgie digestive et oncologique, Lyon, France;5. Hospices Civils de Lyon, service de recherche et d’épidémiologie cliniques, Lyon, France;6. Eurobiodev, 2040, avenue du Père-Soulas, 34090 Montpellier, France |
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| Abstract: | Seven patients with fibrolamellar hepatoma were examined with computed tomography (CT), ultrasonography and angiography. On CT the tumours were large, of low attenuation, had a well-defined edge and some contained areas of calcification or necrosis. Ultrasonography revealed well-defined masses of mixed echogenicity, occasionally involving the portal vein. In one patient there was dilatation of the intrahepatic biliary tree. Arteriography showed vascular tumours with involvement of the portal vein in five cases and compression of the inferior vena cava in five cases. CT and ultrasonography are the most useful radiological investigations for suggesting the diagnosis of fibrolamellar hepatoma which should be considered in the case of any large solitary well-defined hepatic tumour in the noncirrhotic liver of a young person. |
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