中国部分地区无偿献血者梅毒感染情况比较分析

目的了解中国部分地区无偿献血者梅毒感染情况,以便采取相应有效的措施,阻断经血液传播梅毒。方法从文献数据库中收集哈尔滨、银川、宝鸡、枣庄、广州、南昌、益阳等城市及海南省2006~2008年无偿献血者梅毒感染情况的报道文献,汇同成都市血液中心同时段成都市无偿献血者梅毒感人情况的调查结果,采用统计软件spss17.0进行卡方检验,比较分析这些地方的献血者梅毒感染状况。结果 2006~2008年,9地每年无偿献血者梅毒抗体阳性检出率分别为0.21%~1.11%、0.20%~0.98%和0.06%~1.07%(P<0.05),9地每年合计梅毒抗体阳性检出率分别为0.59%(3 502/592 445)、0.56%(3 697/654 361)和0.57%(4 077/714 584);省会城市与其他地区,献血者每年的梅毒抗体阳性率分别为0.59%(2 890/488 593)vs0.59%(613/103 852),0.55%(2 966/535449)vs0.61%(731/118 912)(P<0.05),0.56%(3 246/580 973)vs0.62%(831/133 611)(P<0.05),3年合计献血者梅毒抗体阳性率二者分别为0.57%(9 102/1 605 015)vs0.61%(2 174/356 375)(P<0.05);3年间每年北方地区与南方地区献血者的梅毒抗体阳性率分别为0.78%(1 006/128 900)vs0.54%(2 496/463 545)(P<0.05),0.76%(1 158/152 144)vs0.51%(2 539/502 217)(P<0.01),0.81%(1 363/167 854)vs0.50%(2 714/546 730)(P<0.01)。结论本组资料显示中国各地区献血者梅毒感染阳性率不同,省会城市低于其他地区,北方地区高于南方地区。3年间各地献血者总的梅毒抗体阳性检出率略有降低,说明无偿献血中的梅毒疫情得到了一定控制,但梅毒抗体仍然是血液报废的原因之一。

Treponema pallidum infection among voluntary blood donors in certain domestic districts,China

Objective To investigate Treponema pallidum(TP) infection rate among voluntary blood donors during 2006 to 2008 in certain districts in China.Methods TP infection rate of Ha Erbin,Yinchuan,Baoji,Zaozhuang,Guangzhou,Nanchang,Yiyang,Chengdu and Hainan blood donors were collected from database.And χ2 test in the SPSS 17.0 software was applied to compare the TP infection among these districts.Results From 2006 to 2008,the positive rates of TP rubella antibody in those 9 districts each year were 0.21%～1.11%、0.20%～0.98% and 0.06%～1.07%(P<0.05).The total positive rates of TP rubella antibody in those 9 districts were 0.59%(3 502/592 445)、0.56%(3 697/654 361)and 0.57%(4 077/714 584).Comparing the positive rate of TP rubella antibody between provincial capitals and other districts,the positive rate of TP rubella antibody each year were 0.59%(2 890/488 593) vs 0.59%(613/103 852),respectively;0.55%(2 966/535 449) vs 0.61%(731/118 912),respectively(P<0.05);0.56%(3 246/580 973) vs 0.62%(831/133 611),respectively(P<0.05).And the total positive rate of TP rubella antibody during the three years were 0.57%(9 102/1 605 015) vs 0.61%(2 174/356 375)(P<0.05).Over the 3 years,the TP rubella antibody positive detection rate of northern and southern districts were 0.78%(1 006/128 900) vs 0.54%(2 496/463 545)(P<0.05),0.76%(1 158/152 144) vs 0.51%(2 539/502 217)(P<0.01),0.81%(1 363/167 854) vs 0.50%(2 714/546 730)(P<0.01).Conclusion The TP infection rate of provincial capitals are lower than other districts.And the TP infection rate of northern cities are higher than southern cities.And from 2006 to 2008,the total positive rate of TP antibody declined slightly.