丹芪祛瘀止痛颗粒质量标准的研究

目的:提高丹芪祛瘀止痛颗粒的质量标准。方法:采用薄层色谱法对丹芪祛瘀止痛颗粒中的黄芪、黄连、白芍进行定性鉴别;采用HPLC同时测定方中芍药苷和丹酚酸B的含量。结果:薄层色谱图斑点清晰,阴性对照无干扰。对含量测定方法进行了稳定性、精密度及重复性等方法学考察,结果符合要求。结论:方法简便可行,结果准确可靠,重复性好,可作为本制剂的质量控制方法。

Studies on Quality Standard for Danqi Quyu Zhitong Granules

Objective: To advance the quality standard of Danqi Quyu Zhitong granules. Method: Radix Astragali,Rhizoma Coptidis and Radix Paeoniae Alba in this medicine were identified by TLC.The paeoniflorin and salvianolic acid B were identified by HPLC. Result: The spots on TLC plates were clear without interference in the blank reference.The stability,precision and reproducibility of the determined method were studied. Conclsion: The method is simple,reliable and accurate,and can be applied as the quality control method of Danqi Quyu Zhitong granules.