| 粒巨细胞集落刺激因子预防化疗后口腔溃疡的研究 |
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| 引用本文： | 赵蕊,顾文英,藏金菊,朱桔,刘存娣,李旬.粒巨细胞集落刺激因子预防化疗后口腔溃疡的研究[J].齐鲁护理杂志,2003,9(1):1-2. |
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| 作者姓名： | 赵蕊 顾文英 藏金菊 朱桔 刘存娣 李旬 |
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| 作者单位： | 上海复旦大学肿瘤医院,上海,200002 |
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| 基金项目： | 复旦大学肿瘤医院 1 999年度护理科研基金资助项目 |
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| 摘 要： | 目的：为减轻化疗所致口腔溃疡给患带来的痛苦，探讨预防化疗所致口腔溃疡的有效方法。方法：63例患随机分成两组，从第2疗程化疗中开始，A组用3％的碳酸氢钠漱口液，B组用粒巨细胞集落刺激因子（GM－CSF）漱口液。结果：患对两组漱口液均能耐受使用，但两组相比，粒巨细胞集落刺激因子漱口液改善口爱粘膜反应程度效果优于碳酸氢钠漱口液。结论：粒巨细胞集落刺激因子对化疗所致口腔溃疡有显疗效，可减轻化疗所致口腔溃疡患的痛苦，值得推广使用。
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| 关 键 词： | 粒巨细胞集落刺激因子 预防 化疗 口腔溃疡 研究 |
| 文章编号： | 1006-7256(2003)01-0001-02 |
| 修稿时间： | 2002年11月27 |
Clinical research about prevention from oral ulcer induced by chemotherapy by granulomacrocytic colony stimulating factors (GM - CSF) |
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| ZHAO Rui,GU Wen-ying,ZANG Jin-ju,et al.Clinical research about prevention from oral ulcer induced by chemotherapy by granulomacrocytic colony stimulating factors (GM - CSF)[J].Journal of Qilu Nursing,2003,9(1):1-2. |
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| Authors: | ZHAO Rui GU Wen-ying ZANG Jin-ju |
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| Abstract: | Objective:To explore effective method to prevent oral ulcer from chemotherapy.Method:63 cases were divided into two groups.A:3% sodium bicarbonate gargle began from second therapy stage,B:GM-CSF gargle group.Result:17 cases in group B with oral mucosa reaction more than 2 grades lower,15 cases in 40 of group A acquired mucosa reaction more than two grades lower;B show superior to A.Conclusion:GM-CSF is effective in relieving oral ulcer from chemotherapy is worthy of spreading. |
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| Keywords: | GM-CSF 3% sodium bicarbonate Chemotherapy Oral ulcer |
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