Functional Abnormalities of Neutrophils in Childhood Acute Leukemia: Decreased Myeloperoxidase and 13-Glucuronidase Contents and Their Release |
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| Authors: | Yoji Hara M.D. |
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| Affiliation: | Department of Pediatrics, Shinshu University School of Medicine, Matsumoto |
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| Abstract: | The myeloperoxidase and β-glucuronidase contents of neutrophils as total index (T index) and their release induced by formyl-methionyl-leucyl-phenylalanine (FMLP) as stimulation release index (SR index) and percent enzyme release index (%ER index) were assayed in children with acute leukemia at various stages. T indexes and SR indexes of these enzymes and %ER index of p-glucuronidase were significantly decreased at onset or relapse (P
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| Keywords: | Neutrophils, Myeloperoxidase, β-glucuronidase, Infection, Acute Leukemia. |
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