冠状动脉部分血管闭塞发生心肌梗死的临床相关因素分析

目的:分析冠状动脉部分血管闭塞发生心肌梗死的临床相关因素.方法:回顾性总结56例冠状动脉造影显示部分血管完全闭塞的患者,将其按临床症状分为A组(有心肌梗死发生)和B组(无心肌梗死发生),比较两组患者的临床特点.结果:与临床心肌梗死相关的因素包括糖尿病、心绞痛病史、高胆固醇、高低密度脂蛋白、吸烟史、长期规律性用药史及侧支循环情况、心电图改变等均为局限性因素(P<0.05).结论:冠状动脉造影血管完全闭塞有不同的临床表现形式,有心绞痛病史(＞6个月)、长期规律性药物治疗、血糖和血脂控制较好、不吸烟的患者临床上可发生无症状心肌梗死,可能与上述因素能促进冠状动脉侧支循环形成及缺血预适应机制等有关.

Risk factors for coronary artery occlusion-induced myocardial infarction

Objective: To study the related factors of artery occlusion induced cardiac infarction. Methods: The coronary angiography data of 56 patients with total artery occlusion were retrospectively studied. The patients were divided into 2 groups: Group A with cardiac infarction, Group B without cardiac infarction, and the clinical features of the 2 groups were compared. Results: It was found that diabetes mellitus, anginal pectoris, hypercholesterolemia, high and low density lipoprotein, smoking, long term medication, collateral circulation, and changes of electrocardiogram presentation were all related factors of infarction( P <0.05). Conclusion: It is indicated that coronary artery occlusion diagnozed by coronary arteriography has different kinds of clinical features. Asymptomatic cardiac infarction may be associated with angina pectoris(>6 months), long term medication, well controlled blood glucose and lipoprotein, and non smoking, probably because these factors can improve the collateral circulation and induce ischemia preconditioning.