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Prevention of local tumor growth with paclitaxel-loaded microspheres |
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| Authors: | Azouz Solomon M Walpole Joseph Amirifeli Sepideh Taylor Kendra N Grinstaff Mark W Colson Yolonda L |
| Affiliation: | a Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Mass b Departments of Biomedical Engineering and Chemistry, Boston University, Boston, Mass |
| Abstract: | |
| Keywords: | BSA, bovine serum albumin DMEM, Dulbecco's modified Eagle's medium DMSO, dimethyl sulfoxide ELISA, enzyme-linked immunosorbent assay FBS, fetal bovine serum IC50, amount of paclitaxel necessary to inhibit the growth of lung cancer tumor cells by 50% LLC, Lewis lung carcinoma cell MTT, 3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide Pax-PLGA, paclitaxel-loaded poly-(D,L-lactic-co-glycolic acid) PI, propidium iodide SEM, scanning electron microscopy |
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