| 通鼻胶囊对豚鼠变态反应性鼻炎的抑制作用 |
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| 引用本文： | 于海玲,曲香芝,洪淳赞.通鼻胶囊对豚鼠变态反应性鼻炎的抑制作用[J].延边医学院学报,2005,28(3):167-170. |
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| 作者姓名： | 于海玲 曲香芝 洪淳赞 |
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| 作者单位： | [1]延边大学基础医学院药理学教研室 [2]延边大学医院临床药理学研究室,吉林延吉133000 |
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| 摘 要： | 目的]探讨通鼻胶囊对豚鼠变态反应性鼻炎的抑制作用.方法]给予2,4-二异氰酸甲苯酯橄榄油溶液制备豚鼠变态反应性鼻炎模型,灌胃给予通鼻胶囊,取胸腺及脾脏称其质重,鼻黏膜行光学显微镜及电子显微镜观察.结果]通鼻胶囊明显抑制变态反应性鼻炎豚鼠胸腺增生,对脾脏质量无明显影响,使豚鼠鼻黏膜的组织结构及超微病理形态基本恢复正常.结论]通鼻胶囊对豚鼠变态反应性鼻炎有一定的抑制作用.
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| 关 键 词： | 鼻炎 药物疗法 豚鼠 |
| 文章编号： | 1000-1824(2005)03-0167-04 |
| 收稿时间： | 04 28 2005 12:00AM |
| 修稿时间： | 2005年4月28日 |
Inhibitory effects of Tongbi capsule on allergic rhinitis in guinea pigs |
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| YU Hal-ling, QU Xiang-zhi, HONG Chun-zan.Inhibitory effects of Tongbi capsule on allergic rhinitis in guinea pigs[J].Journal of Medical Science Yanbian University,2005,28(3):167-170. |
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| Authors: | YU Hal-ling QU Xiang-zhi HONG Chun-zan |
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| Abstract: | OBJECTIVE To study the therapeutic effects of Tongbi capsule on allergic rhinitis in guinea pigs. METHODS The models of allergic rhinitis were induced by TDI olive oil, and given Tongbi capsule. Then the spleen and thymus of rats were removed and weighed, and mucous membrane of nose was taken out and observed by light microscope and electron microscope. RESULTS The thymus hyperplasia of allergic rhinitis in guinea pigs was obviously inhibited by Tongbi capsule, but the weight of spleen wasn' t affected, and the tissue structure and ultrastructure were returned to normal. CONCLUSION Tongbi capsule has inhibitory action on allergic rhinitis. |
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| Keywords: | rhinitis drug therapy guinea pigs |
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