国产氯吡格雷治疗急性冠脉综合征的有效性和安全性

目的：比较国产氯吡格雷（泰嘉,Talcom）和进口氯吡格雷（玻立维,Plavix）治疗急性冠脉综合征的有效性和安全性。方法：将166例急性冠脉综合征患者随机分为两组,泰嘉治疗组和玻立维治疗组各83例,随访12个月以上,观察冠脉造影情况和主要心血管事件发生率。结果：玻立维治疗组再发心绞痛、非致命性心肌梗死、再次血运重建、支架内亚急性血栓和再狭窄及死亡的发生率分别为4.8%、1.2%、1.2%、1.2%、2.4%和1.2%,而在泰嘉治疗组分别为3.6%、1.2%、1.2%、1.2%、2.4%和1.2%,差异无统计学意义（P〉0.05）。结论：与进口氯吡格雷相似,国产氯吡格雷治疗急性冠脉综合征是安全、有效的

Efficacy and safety of Domestic Clopidogrel for acute coroanry syndrome

Objectives: To compare the efficacy and safety of Domestic Clopidogrel(Talcom) with imported Clopidogrel(Plavix) in patients with acute coronary syndrome(ACS).Methods: 166 patients with ACS were randomly invided into Talcom group(n=83) and Plavix group(n=83).During over 12 months follow-up,coronary angiographic outcome and major adverse cardiac events were observed.Results: The ratio of recurrent angina pectoris,non-fatal myocardial infarction,revascularization,in-stent thrombosis and restenosis and mortali...