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营养不良风险的慢性乙型肝炎患者甲胎蛋白、高尔基体糖蛋白73表达分析
引用本文:翁田波,谭奕洲,周桂华,胡凤玉,陈秋香,陈星,陈冉. 营养不良风险的慢性乙型肝炎患者甲胎蛋白、高尔基体糖蛋白73表达分析[J]. 中国医药导报, 2011, 8(11): 23-25
作者姓名:翁田波  谭奕洲  周桂华  胡凤玉  陈秋香  陈星  陈冉
作者单位:1. 广州市第八人民医院营养科,广东广州,510060
2. 广州市第八人民医院检验科,广东广州,510060
3. 广州花都区雅瑶医院外科,广东广州,510080
4. 广州市第八人民医院肝病科,广东广州,510060
摘    要:目的:研究应用营养筛查评分简表(NRS2002)评分在甲胎蛋白(AFP)、高尔基体糖蛋白73(GP73)高表达的患者中的应用价值。方法:对206例肝炎患者体重指数(BMI)、白蛋白、AFP、GP73的测定,利用NRS2002评分简表对患者进行评分,将患者分成营养风险组(A组)和非营养风险组(B组),采用统计学方法对A、B组两组患者的AFP、GP73表达进行分析。结果:营养风险组所检测的AFP、GP73高表达率显著高于非营养风险组(P〈0.05);营养风险组的CHB、肝硬化、原发性肝癌(PHC)患者AFP、GP73的表达逐渐增加;NRS2002分值越高,AFP、GP73表达亦增高。结论:结合NRS2002评分能更多地将无AFP、GP73高表达的患者被正确区分,从而提高AFP、GP73高表达的检出率。

关 键 词:慢性活动性肝炎  营养风险筛查(2002)  甲胎蛋白  高尔基体糖蛋白73

Analysis of the Expression of GP73 and AFP in Chronic Hepatitis B Patients with Malnutrition Risks
WENG Tianbo,TAN Yizhou,ZHOU Guihua,HU Fengyu,CHEN Qiuxiang,CHEN Xing,CHEN Ran. Analysis of the Expression of GP73 and AFP in Chronic Hepatitis B Patients with Malnutrition Risks[J]. China Medical Herald, 2011, 8(11): 23-25
Authors:WENG Tianbo  TAN Yizhou  ZHOU Guihua  HU Fengyu  CHEN Qiuxiang  CHEN Xing  CHEN Ran
Affiliation:1.Nutritional Department,the Eighth People′s Hospital of Guangzhou City,Guangzhou 510060,China;2.Department of Clinical Laboratory,the Eighth People′s Hospital of Guangzhou City,Guangzhou 510060,China;3.Surgercal Department,Yayao Hospital of Huadu District in Guangzhou City,Guangzhou 510080,China;4.Department of Hepatopathy,the Eighth People’s Hospital of Guangzhou City,Guangzhou 510060,China
Abstract:Objective: To investigate the value of using NRS2002 to grade patients with high expression of AFP and GP73.Methods: With the help of NRS2002,the patients were classified into nutrition risk group(A) and non-nutrition group(B) after testing the BMI,albumin,AFP,and GP73 of 206 hepatitis patients.By means of statistical methods,the expression of AFP and GP73 of these two groups will be analyzed.Results: The expression rate of AFP and GP73 detected in group A were remarkably higher than that in group B(P<0.05)...
Keywords:CHB  Nutritional risk screening(NRS2002)  AFP  GP73  
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