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阿魏酸钠对肺动脉高压右心功能不全治疗效果的临床研究
引用本文:娄长芹,王奉德.阿魏酸钠对肺动脉高压右心功能不全治疗效果的临床研究[J].中国医药导报,2011,8(9):64-65.
作者姓名:娄长芹  王奉德
作者单位:吉林省吉化集团公司总医院心内科,吉林吉林,132000
摘    要:目的:探讨阿魏酸钠(SF)对肺动脉高压右心功能不全的治疗效果。方法:将肺动脉高压右心功能不全患者47例随机分为SF组(常规治疗+阿魏酸钠)和常规治疗组(对照组),治疗组除常规治疗外加阿魏酸钠片100 mg,tid,2.5个月后行心功能改善情况评定,行血气分析比较氧分压、血氧饱和度变化,行心脏超声检查测量右室横径,根据三尖瓣反流估测肺动脉压。结果:①治疗后两组心功能改善的有效率分别为91.7%、65.2%,差异有统计学意义(P〈0.05);②治疗SF组氧分压提高,肺动脉压降低,差异有统计学意义(P〈0.05)。结论:阿魏酸钠可改善肺动脉高压患者的右心功能,为肺动脉高压右心功能不全治疗的安全、有效的药物之一。

关 键 词:肺动脉高压  右心功能不全  阿魏酸钠

Clinical study of Sodium Ferulate on right ventricular dysfunction with pulmonary hypertension
LOU Changqin,WANG Fengde.Clinical study of Sodium Ferulate on right ventricular dysfunction with pulmonary hypertension[J].China Medical Herald,2011,8(9):64-65.
Authors:LOU Changqin  WANG Fengde
Institution:LOU Changqin,WANG Fengde Department of Cardiology,Jihua Group Company General Hospital,Jilin Province,Jilin 132000,China
Abstract:Objective:To investigate effects of Sodium Ferulate(SF) on right ventricular dysfunction in pulmonary hypertension.Methods:47 patients pulmonary hypertension with right ventricular dysfunction were randomly divided into SF group(conventional therapy + SF) and conventional treatment group(control group),the treatment group on the basis of routine treatment plus oral Sodium Ferulate 100 mg,tid,improving situation of cardiac function after 2.5 months was assessed,blood gas analysis and oxygen partial pressure ...
Keywords:Pulmonary hypertension  Right ventricular failure  Sodium Ferulate  
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