人胰岛素类似物联合治疗与胰岛素泵治疗初诊2型糖尿病的对比研究

目的：观察门冬胰岛素（诺和锐）联合甘精胰岛素（来得时）与用胰岛素泵强化治疗伴明显高血糖的初诊2型糖尿病的疗效及成本。方法：将80例初诊伴明显高血糖的2型糖尿病患者随机分为A、B两组，每组40例。A组三餐前皮下注射诺和锐联合睡前皮下注射来得时；B组利用胰岛素泵加诺和锐持续泵入及分别注射三餐前大剂量。比较两组患者治疗后血糖控制及低血糖发生情况、血糖达标时间、成本及每日胰岛素用量。结果：治疗后两组患者血糖、胰岛素用量、血糖达标时间差异无统计学意义（均P〉O．05），血糖达标时治疗成本B组明显高于A组（P〈O．01）。结论：门冬胰岛素联合甘精胰岛素强化治疗与胰岛素泵治疗效果相当，且更经济。

Comparison of insulin analogue combination treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients

Objective: To observe the effects and the cost of insulin analogue combination treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients with severe hyperglycemia.Methods: 80 newly diagnosed type 2 diabetic patients with severe hyperglycemia were divided into group A and group B in random,with 40 patients in each group.Group A was treated with insulin aspart subcutaneous injections before meals and the insulin glargine subcutaneous injections at bedtime.Group B was treated with contin...