| 曲美他嗪对扩张型心肌病心力衰竭治疗效果的临床观察 |
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| 引用本文： | 娄长芹,李冬梅,王雁先.曲美他嗪对扩张型心肌病心力衰竭治疗效果的临床观察[J].中国医药导报,2011,8(7):64-65. |
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| 作者姓名： | 娄长芹 李冬梅 王雁先 |
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| 作者单位： | 北华大学第二附属医院(吉化总医院)循环内科,吉林吉林,132022 |
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| 摘 要： | 目的：观察曲美他嗪（TMZ）对扩张型心肌病（DCM）患者心力衰竭的临床疗效。方法：42例DCM伴中重度心力衰竭患者随机分为TMZ治疗组（TMZ组）和常规治疗组（对照组）。对照组给予规范的纠正心力衰竭治疗，TMZ组在常规治疗的基础上加用TMZ，每次20mg，每日3次，疗程半年，测定患者用药前后6min步行距离及利用心脏彩色多普勒超声测定患者左室射血分数（LVEF）、左室舒张末期内径（LVEDd）的变化。结果：治疗半年后，TMZ组6min步行距离显著优于对照组（P〈0．05），超声心动图LVEF明显提高（P〈0．05），LVEDd显著缩小。结论：曲美他嗪可以改善DCM患者的心功能，可以用作DCM的辅助治疗药物。
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| 关 键 词： | 曲美他嗪 扩张型心肌病 心力衰竭 心功能 |
Clinical therapeutic effect of Trimetazidine on heart failure patients with dilated cardiomyopathy |
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| LOU Changqin,LI Dongmei,WANG Yanxia.Clinical therapeutic effect of Trimetazidine on heart failure patients with dilated cardiomyopathy[J].China Medical Herald,2011,8(7):64-65. |
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| Authors: | LOU Changqin LI Dongmei WANG Yanxia |
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| Institution: | LOU Changqin,LI Dongmei,WANG Yanxia [Circulating Medicine,Beihua University of the 2nd Affiliated Hospital(Jihua General Hospital),Jilin 132022,China] |
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| Abstract: | Objective: To observe the clinical therapeutic effect of Trimetazidine(TMZ) on dilated cardiomyopathy(DCM) patients with clinical heart failure.Methods: 42 cases of DCM with severe heart failure were randomly divided into TMZ treatment group(TMZ group) and conventional treatment group(Control group).Control group received standard therapy to treat heart failure,TMZ group on the basis of routine treatment plus TMZ,every time 20 mg,3 times a day,a course of six months.Before and after treatment,6 min walking ... |
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| Keywords: | Trimetazidine Dilated cardiomyopathy Heart failure Cardiac function |
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