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早产儿支气管肺发育不良危险因素的探讨
引用本文:李源斌,王爱平,李卫东. 早产儿支气管肺发育不良危险因素的探讨[J]. 中国医药导报, 2011, 8(10): 52-54
作者姓名:李源斌  王爱平  李卫东
作者单位:1. 南方医科大学附属小榄医院儿科,广东中山,528415
2. 昆明市儿童医院新生儿科,云南昆明,650100
摘    要:目的:调查早产儿支气管肺发育不良(BPD)发病的危险因素,为其防治提供理论依据。方法:回顾性分析2006年1月~2010年12月在我院及昆明市儿童医院新生儿病房住院的早产儿430例,分析胎龄、出生体重等17种可能的相关因素与BPD的关系。结果:430例早产儿中,45例发生BPD,发病率为10.47%。单因素分析显示,母亲有胎膜早破、产道感染、产前应用糖皮质激素、患儿为试管婴儿、男婴、胎龄〈32周、出生体重〈1 500 g、出生时血pH〈7.20、患有呼吸窘迫综合征、感染性肺炎、呼吸暂停、动脉导管开放、败血症、应用机械通气和肺泡表面活性物质治疗等为潜在危险因素。多因素分析显示:胎龄〈32周、出生体重〈1 500 g、感染性肺炎、动脉导管开放和机械通气等为BPD发病的独立危险因素。结论:早产儿BPD发病的潜在危险因素众多,其中胎龄〈32周、出生体重〈1 500 g、感染性肺炎、动脉导管开放和机械通气等为BPD发病的独立危险因素。

关 键 词:支气管肺发育不良  危险因素  早产儿

Clinical study on risk factors for bronchopulmonary dysplasia in premature infants
LI Yuanbin,WANG Aiping,LI Weidong. Clinical study on risk factors for bronchopulmonary dysplasia in premature infants[J]. China Medical Herald, 2011, 8(10): 52-54
Authors:LI Yuanbin  WANG Aiping  LI Weidong
Affiliation:LI Yuanbin1,WANG Aiping 2,LI Weidong1 1.Department of Pediatrics,the Affiliated Xiaolan Hospital of Southern Medical University,Zhongshan 528415,China,2.Neonatal Department,the Children's Hospital of Kunming City,Kunming 650100
Abstract:Objective:To investigate the risk factors for bronchopulmonary dysplasia(BPD) in premature infants and provide a basis for its prevention and treatment.Methods:430 premature infants admitted to neonatal intensive care units(NICU) of Children's Hospital of Kunming City and our hospital from January 2006 to December 2010 were investigated by a retrospective study.The relationship between 17 associated factors including gestational age(GA),birth weight(BW) and BPD were analyzed.Results:Among 430 cases of prema...
Keywords:Bronchopulmonary dysplasia  Risk factors  Premature infants  
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