高血压病患者眼底血管造影定量分析与血液流变学的关系

对高血压病不同时期患者共80例进行了眼底视网膜荧光血管造影定量分析和血液流变学检查。结果显示：随着高血压分期级别的增加，眼底血管造影定量指标：动脉显影时间、静脉充盈时间、毛细血管交换时间增加．毛细血管密度减少，血液流变学指标：全血比粘度、血球压积、红细胞电泳时间、红细胞聚集指数、全血还原比粘度也增加，并且血管造影定量值与血液流变学指标有显著相关性（r＝0．312～0．626P＜0．05和0．01）。提示高血压靶器官损害下不但表现在微血管血液动力学方面，而且血液流变学也有改变，它们共同造成靶器官损害。

A Study of the Relationship Between Fundus Angiography Quantitative Analysis and Hemorrheology in Patients with Hypertension

80 patients with essential hypertension in various stages were examined using nuorescent fundus retina angiography quantitative analysis and hemorrheology. The results demonstrated that with the increase of hypertension stages,the artery developing time (ADT),vein fulling time (VFT),capillary exchangingtime (CET)and hemorrheology target:whole blood viscosity,hematocrit,red blood cell electrophoresis time,red blood cell glutination index and whole b1ood restoring viscosity all increased. And there is a significant relationship between hemorrheology target and angiography quantitative value (r=0. 312-0. 626, P<0.05 and0.01). This suggested that hemodynamics and hemorrheology abnormality resulted in target organ damage ofhypertension.