| 槲皮素对人肝癌细胞SMMC7721增殖的影响 |
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| 引用本文： | 白艳婷,张丽娜,潘素琼,李小军. 槲皮素对人肝癌细胞SMMC7721增殖的影响[J]. 解放军药学学报, 2001, 17(2): 64-66 |
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| 作者姓名： | 白艳婷 张丽娜 潘素琼 李小军 |
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| 作者单位： | 中国人民解放军成都军区总医院,药学部 |
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| 摘 要： | 目的：研究槲皮素人肝癌细胞SMMC7721生长抑制的影响。方法：采用^3H-TdR掺入法，MTT检测法和双层琼脂集落形成实验，观察了肝癌细胞的生长变化。结果：槲皮素对人肝癌细胞SMMC77231有显的抑制生长及增殖，并能使肝癌细胞出现脱落死亡，DNA生成物减少，肝癌细胞SMMC7721集落形成率降低。结论：本实验研究提示，槲皮素对肝癌细胞SMMC7721具有较强的抑制生长及增殖性，并可能用于对肿瘤的协同的治疗研究。
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| 关 键 词： | 槲皮素 肝癌细胞 生长抑制 |
| 文章编号： | 1008-9926(2001)02-0064-03 |
| 修稿时间： | 2000-06-14 |
Effects of Quercetin on Proliferation of Hepatic Cancer Line SMMC7721 |
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| BAI Yan-Ting,ZHANG Li-Na,PAN Su-qiong,LI Xiao-Jun. Effects of Quercetin on Proliferation of Hepatic Cancer Line SMMC7721[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2001, 17(2): 64-66 |
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| Authors: | BAI Yan-Ting ZHANG Li-Na PAN Su-qiong LI Xiao-Jun |
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| Abstract: | Aim To study the inhibition effects of quercetin on human hepatic Cancer line SMMC7721.Methods The growth changes of hepatic cancer cells were observed by 3 H-TDR uptake test,MTT method and Agar clone formation test.Results Quercetin had a significant inhibition to growth and proliferation of human hepatic cancer line SMMC7721.The cancer cells treated by quercetion occurred the phenomenon of death,reduction of DNA,and decrease of clone formation rate.Conclusion Quercetin is an efficient anti-cancer drug and can be used in the study of clinical therapy. |
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| Keywords: | Quercetin Hepatic cancer cells Inhibition proliferation |
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