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Contribution of vascular endothelial growth factor to the Nottingham prognostic index in node-negative breast cancer
Authors:Coradini D  Boracchi P  Daidone M G  Pellizzaro C  Miodini P  Ammatuna M  Tomasic G  Biganzoli E
Affiliation:Unità Operativa Determinanti Biomolecolari nella Prognosi e Terapia, Università degli Studi di Milano, Milan, Italy.
Abstract:The prognostic contribution of intratumour VEGF, the most important factor in tumour-induced angiogenesis, to NPI was evaluated by using flexible modelling in a series of 226 N-primary breast cancer patients in which steroid receptors and cell proliferation were also accounted for. VEGF provided an additional prognostic contribution to NPI mainly within ER-poor tumours.
Keywords:flexible modelling   N-negative primary breast cancer   NPI   VEGF
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