Contribution of vascular endothelial growth factor to the Nottingham prognostic index in node-negative breast cancer |
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Authors: | Coradini D Boracchi P Daidone M G Pellizzaro C Miodini P Ammatuna M Tomasic G Biganzoli E |
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Affiliation: | Unità Operativa Determinanti Biomolecolari nella Prognosi e Terapia, Università degli Studi di Milano, Milan, Italy. |
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Abstract: | The prognostic contribution of intratumour VEGF, the most important factor in tumour-induced angiogenesis, to NPI was evaluated by using flexible modelling in a series of 226 N-primary breast cancer patients in which steroid receptors and cell proliferation were also accounted for. VEGF provided an additional prognostic contribution to NPI mainly within ER-poor tumours. |
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Keywords: | flexible modelling N-negative primary breast cancer NPI VEGF |
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