| 羟基磷灰石的生物学基础及临床应用 |
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| 引用本文： | 陈兵,司徒朴,王迎军,刘康时,黄励知,肖能坎,熊明根,顾浩,梁雄,包新民,黎梅兰.羟基磷灰石的生物学基础及临床应用[J].南方医科大学学报,1995(3). |
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| 作者姓名： | 陈兵 司徒朴 王迎军 刘康时 黄励知 肖能坎 熊明根 顾浩 梁雄 包新民 黎梅兰 |
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| 作者单位： | 第一军医大学第二附属医院，华南理工大学无机化学系 |
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| 摘 要： | 我院与华南理工大学共同研制了一种块状羟基磷灰石人工骨（ＢＨＡＢ）。在小白鼠体内进行了急性毒性试验，体外微量细胞毒性试验，溶血试验。兔皮下埋值试验及兔下颌骨埋植试验。结果证明该材料无毒性，不致的，不引起炎症反应，具有良好的生物相容性，并能与软、硬组织形成紧密的结合。在１４例颌面整形的临床应用中取得满意的结果。
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| 关 键 词： | 羟基磷灰石，人工骨，生物相容性材料，颌面 |
Study of the biological basis of block hydroxyapatite artificial bone
and the clinical application in maxillofacial bone |
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| Chen
Bing,Situ Pu,Wang Yingiun,et al..Study of the biological basis of block hydroxyapatite artificial bone
and the clinical application in maxillofacial bone[J].Journal of Southern Medical University,1995(3). |
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| Authors: | Chen
Bing Situ Pu Wang Yingiun |
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| Institution: | Chen
Bing,Situ Pu,Wang Yingiun,et al.Department of Plastic
Surgery,zhujiang Hospital,The First Military Medical University. |
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| Abstract: | uanan Scince and Engneering University and our department
developed a kind of block hydroxyap-atite artificial bone(BHAB).Acute
toxicity test in mice,cell trace toxicity test in vitro,hemolytic
test,rabbit subcutaneous implantation test,rabbit mandibular
implantation test all showed that the materialhad no toxicity, no
antigenicity,no induction of inflammation,and had an extremely good
biocompatibi-lity. It could form a close union with both the soft and
hard tissue. 14 cases were reported. |
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| Keywords: | Hydroxyapatite:artificial bone biocompatible material maxillofacial |
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