| 电针对佐剂性关节炎大鼠脾细胞IL—1和IL—2活性的影响 |
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| 引用本文： | 赵仓焕,王虹英,杨介宾,宋开源,罗永芬,梁繁荣.电针对佐剂性关节炎大鼠脾细胞IL—1和IL—2活性的影响[J].上海针灸杂志,2001,20(2):34-36. |
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| 作者姓名： | 赵仓焕 王虹英 杨介宾 宋开源 罗永芬 梁繁荣 |
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| 作者单位： | 1. 暨南大学医学院第一附属医院针灸科
2. 成都中医药大学针推学院 |
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| 摘 要： | 目的 为了探讨电针（EA）对炎症痛镇痛的外周机制，观察EA对佐剂性关节炎（AA）大鼠脾细胞中细胞因子白细胞介素1（IL－1）和白细胞介素2（IL－2）活性的影响。方法 用福氏完全佐剂造成佐剂性关节炎，电针刺激悬钟和昆仑穴，用H^3-TdR掺入法和MTT显色法分别检测IL－1和IL－2的活性。结果 EA对AA大鼠镇痛的同时，能够提高细胞因子IL－1和IL－2的活性。结论 EA对炎症痛镇痛的外周机制与其提高细胞因子IL－1和IL－2的活性有关。
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| 关 键 词： | 佐剂性关节炎 白细胞介素1 白细胞介素2 镇痛 电针疗法 实验研究 |
| 文章编号： | 1005-0957(2001)02-0034-03 |
| 修稿时间： | 2000年9月10日 |
EFFECT OF ELECTRO-ACUPUNCTURE ON ACTIVITY OF IL-1 AND IL-2 IN SPLEEN CELL IN ADJUVANT ARTHRITIS RAT |
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| ZHAO Cang huan ,WANG Hong ying ,YANG Jie bin ,SONG Kai yuan ,LUO Yong fen ,LIANG Fan rong.EFFECT OF ELECTRO-ACUPUNCTURE ON ACTIVITY OF IL-1 AND IL-2 IN SPLEEN CELL IN ADJUVANT ARTHRITIS RAT[J].Shanghai Journal of Acupuncture and Moxibustion,2001,20(2):34-36. |
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| Authors: | ZHAO Cang huan WANG Hong ying YANG Jie bin SONG Kai yuan LUO Yong fen LIANG Fan rong |
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| Institution: | ZHAO Cang huan 1,WANG Hong ying 2,YANG Jie bin 3,SONG Kai yuan 3,LUO Yong fen 3,LIANG Fan rong 3 1. First Hospital Affiliated to Medical College of Ji'nan University,Guangzhou,510630,China, 2. Shanghai Institute of Acupuncture an |
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| Abstract: | Objective To probe into peripheral mechanism of electroacupuncture (EA) analgesia, the effect of EA on acitivity of IL 1 and IL 2 in spleen cell in adjuvant arthritis (AA) rat was observed. Methods Freund's complete adjuvant was injected into the right hind paw of art to establish adjuvant arthritis model, then the rat's acupoints Xuanzhong (GB 39) and Kunlun (BL 60) were given EA stimulation, and the H 3 TdR incorporation method and MTT development process were adopted to detect the activity of IL 1 and IL 2. Results EA may not only exert analgesic effect on AA rat, but also raise the activity of IL-1 and IL-2 in spleen cell. Conclusions The peripheral mechanism of EA analgesia is related to raising the activity of cellular factors IL-1 and IL-2. |
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| Keywords: | Electro acupuncture Adjuvant arthritis inflammatory pain IL-1 IL-2 Analgesic |
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