Abstract: | Acute stress was accompanied by reduction of 11-dehydrocorticosterone to corticosterone in male rats. The reverse reaction
predominated during repeated stress and increased after administration of dehydroepiandrosterone sulfate. Treatment with μ-opioid
receptor antagonist naltrexone in a dose of 0.1 mg/kg 20 min before administration of dehydroepiandrosterone sulfate abolished
this effect.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 8, pp. 158–161, August, 2004 |