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三硝基甲苯对小鼠骨髓细胞染色体畸变和微核率的影响
引用本文:李莲姬,吴国用,崔山田,沈美善. 三硝基甲苯对小鼠骨髓细胞染色体畸变和微核率的影响[J]. 延边医学院学报, 1988, 0(3)
作者姓名:李莲姬  吴国用  崔山田  沈美善
作者单位:延边医学院卫生学教研室,延边医学院卫生学教研室,延边医学院卫生学教研室,延边医学院卫生学教研室
摘    要:本文研究了三硝基甲苯对小鼠骨髓细胞染色体畸变和微核率的影响。三硝基甲苯实验组的小鼠骨髓细胞染色体畸变明显增高,且呈现剂量-反应关系,实验组小鼠骨髓嗜多染红细胞微核率明显高于对照组(P<0.001)。这些结果表明,三硝基甲苯是一种致突变物。

关 键 词:三硝基甲苯  染色体畸变  微核率  致突变物

Frequency of Chromosome Aberration and Micronucleus Rate in Cultured Mouse Bone Marrow Cells to 2,4,6-Trinitrotoluene
Li Lianji. Frequency of Chromosome Aberration and Micronucleus Rate in Cultured Mouse Bone Marrow Cells to 2,4,6-Trinitrotoluene[J]. Journal of Medical Science Yanbian University, 1988, 0(3)
Authors:Li Lianji
Affiliation:Department of Hygiene
Abstract:The frequency of chromosome aberration and micronucleus rate in cultured mouse bone marrow cells to 2,4,6-trinitrotoluene was studied.The frequency of chromosome aberration in the mouse bone marrow cells to 2,4,6-trinitrotoluene showed a significant and dose dependent increase. The micornucleus rate of polychromatophilic erythroblast in the cultured mouse bone marrow cells to 2,4,6-trinitrotoluene was significantly higher than in the control(p
Keywords:2  4  6-trinitrotoluene  chromosome aberration  micronueleus rate  mutagen  
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