人工流产对子宫腺肌症发生的影响

目的 分析人工流产次数、时机等对子宫腺肌症(AM)发生的影响.方法 分析2004年1月～2008年12月南通大学附属医院妇产科和2008年1月～12月北京航空中心医院妇产科资料完整AM 306例,研究AM组人流术的时机、次数等细节特点,与其他原因行子宫切除而无AM者(无AM组)156例进行了对照研究.结果 AM组与无AM组平均年龄、平均初潮年龄、第1次人流平均年龄、产次、平均孕次、有宫内节育器伴妊娠等无显著差异(P>0.05).AM组2次或2次以上人流比例(63.1%,27.8%)明显高于对照组(34.6%,3.9%),AM组1次人流者比例(9.2%)明显低于对照组(61.5%)(X2=151.3484,P=0.000,P<0.001).>8周者行人流术发生AM(45.8%,32.4%)明显高于无AM组(13.5%,9.0%),AM组<6周行人流术者比例(3.6%)明显低于对照组(53.2%)(x2=180.8535,P=0.000,P<0.001).钳刮者AM组比例(12.4%)高于无AM组(5.8%)(x2=4.999,P=0.033,P<0.05).结论 多次重复人流、大孕周人流、钳刮是患AM的高危因素.

Artificial Abortion Has Important Effect on the Development of Adenomyosts

Objective To study the factors such as artificial abortion frequency, pregnancy time and so on on development of adeno-myosis (AM). Methods A retrospective analysis was carried in 462 patients who were from the department of gynaecology and obstetrics in Affiliated Hospital of Nantong University and Beijing Aviation Center Hospital from January 2004 to December 2008. The patients were divided into two groups: AM and no - AM. The two groups were compared for abortion frequency, pregnancy time, age, menarche age and so on. Results There were no significant differences between the two groups in age, menarche age, age of the first artificial abor-tion, bearing frequency, IUD with pregnancy and so on(P > 0.05). The proportion of patients with repeated artificial abortion or history of curettage of uterus in AM group was higher than that in the no - AM group. The patients with pregnaney time more than 8 weeks who re-ceived artificial abortion had higher rate of development of AM. Conclusion Repeated artificial abortion, pregnancy time and history of curettage of uterus were the risk factors of development of adenomyosis.