110例肾小球疾病临床病理分析

目的]探讨肾小球疾病临床与病理类型.方法]110例肾小球疾病患者均行肾活检病理学检查.结果]110例肾小球疾病中,原发性肾小球疾病92例,占83.6%.IgA肾病(27.2%)居首位,其次为系膜增生性肾炎(22.8%)和微小病变(19.6%).继发性肾小球疾病患者中sLE居首位,其次为乙肝相关性肾病.结论]肾小球疾病患者进行肾活检十分必要,特别是在治疗和预后判断方面更具有指导意义.

Clinical presentation and pathologic feature of 110 patients with glomerular disease

Objective] To study the relationship between pathological changes and clinical classification of the glomerular disease.Methods] One hundred-ten patients suffered from chronic renal disease were examined by using percutaneous renal biopsy.Result] Among 110 patients,92 cases(83.6%) were primary glomerulonephritis,in which IgA nephropathy(IgAN) was the first of all(27.2%),and then was mesangial proliferative glomerulonephritis(MsPGN)(22.8%) and minimal change disease(MCD)(19.6%).Eighteen cases were secondary glomerulonephritis,whose pathology were mostly constituted of lupus nephritis and hepatitis B virus-associated nephropathy.Conclusion] A renal biopsy was necessary to the patients with glomerular disease,particularly it will play an important role in treatment and prognosis for glomerular disease.