Vogt–Koyanagi–Harada syndrome in a Greenlandic Inuit |
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Authors: | Jens Østergaard Ernst Goldschmidt Nis Andersen |
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Institution: | 1. Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark;2. Eye Doctors in Greenland, ?jenl?gernes Hus, Copenhagen, Denmark |
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Abstract: | Purpose: To report a case of Vogt–Koyanagi–Harada syndrome (VKH) in an Inuit. Methods: We carried out a medical evaluation and human leucocyte antigen (HLA) genotyping. Results: A 36‐year‐old male Inuit developed severely decreased vision, intense headache and vertigo over a 3‐week period. Ocular examination revealed panuveitis with bilateral serous retinal detachment and optic nerve head oedema. There was no history of ocular trauma or evidence suggestive of other disease entities. The patient responded well to high‐dose systemic prednisolone. Vitiligo presented late in the course. Conclusions: This case report describes the first published case of VKH in a patient of Inuit ancestry. The patient was homozygous for HLA‐DR4, a genotype previously associated with VKH. |
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Keywords: | DR4 HLA Inuit uveitis Vogt– Koyanagi– Harada syndrome |
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