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H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1 |
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| Authors: | Christian Magerl,Till Braunschweig,Elisabeth Kremmer,Lin Kristin Koch,Tobias Hö ller,Bernhard Lü scher,Ines Gü tgemann |
| Affiliation: | a Department of Pathology, University of Bonn, Sigmund-Freud-Straβe 25, 53127 Bonn, Germany b Department of Urology, University of Bonn, Sigmund-Freud-Straβe 25, 53127 Bonn, Germany c Department of Pathology, University of Aachen, Pauwelsstraβe 30, 52074 Aachen, Germany d GSF-Institute of Molecular Immunology, Marchioninistraβe 25, 81377 München, Germany e Institute for Biometry, Informatics and Epidemiology, University of Bonn, Sigmund-Freud-Straβe 25, 53105 Bonn, Germany f Department of Biochemistry and Molecular Biology, RWTH Aachen University, Pauwelsstraβe 30, 52057 Aachen, Germany |
| Abstract: | |
| Keywords: | Epigenetic regulation Histone methylation and demethylation H3K4 LSD1 Ash2 |
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