| 短瓣金莲花水溶性化学成分研究 |
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| 引用本文： | 吴丽真,许旭东,杨峻山. 短瓣金莲花水溶性化学成分研究[J]. 中国药学杂志, 2011, 46(10): 745-746 |
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| 作者姓名： | 吴丽真 许旭东 杨峻山 |
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| 作者单位： | 中国医学科学院-北京协和医学院药用植物研究所; |
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| 基金项目： | 十一五“重大新药创制”科技重大专项(2009ZX09301-003); 北京市自然基金面上项目(7082059) |
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| 摘 要： | 目的 研究短瓣金莲花水溶性部位的化学成分。 方法 采用硅胶柱色谱、Sephadex LH-20凝胶色谱、中压及高压半制备色谱等手段分离,并运用现代光谱技术鉴定化合物结构。结果 从短瓣金莲花水部分分离得到4个化合物,分别鉴定为： 2-(3,4-dihydroxyphenyl-2-hydroxyethyl-O-β-D-glucopyranoside(Ⅰ ,2-(3,4-dihydroxyphenyl-ethyl-O-β-D-glucopyranoside（Ⅱ,3,5-dihydroxyphenethyl alcohol 3-O-β-D-glucopyranoside（Ⅲ,菊苣苷 (cichoriin,Ⅳ。 结论 化合物Ⅰ~Ⅳ均为首次从本属植物中分离得到,其中化合物Ⅰ为新的天然产物。
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| 关 键 词： | 短瓣金莲花 毛茛科 2-(3 4-dihydroxyphenyl-2-hydroxyethyl -O-β-D-Glucopyranoside 化学成分 |
| 收稿时间： | 2011-11-11; |
Chemical Constituents of Water Soluble Fraction of Trollius ledebouri Reichb |
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| WU Li-zhen,XU Xu-dong,YANG Jun-shan. Chemical Constituents of Water Soluble Fraction of Trollius ledebouri Reichb[J]. Chinese Pharmaceutical Journal, 2011, 46(10): 745-746 |
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| Authors: | WU Li-zhen XU Xu-dong YANG Jun-shan |
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| Affiliation: | WU Li-zhen,XU Xu-dong,YANG Jun-shan(Chinese Academy of Medical Science,Peking Union Medical College,Institute of Medicinal Plant Development,Beijing 100193,China) |
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| Abstract: | OBJECTIVE To study the chemical constituents of Trollius ledebouri Reichb. METHODS The constituents of Trollius ledebouri were isolated and purified by means of various chromatography techniques,and their structures were identified by modern spectral measures. RESULTS Four components were isolated from the Trollius ledebouri Reichb,and identified as 2-(3,4-dihydroxyphenyl-2-hydroxyethyl-O-β-D-glucopyranoside,2-(3,4-dihydroxyphenyl-ethyl-O-β-D-glucopyranoside,3,5-dihydroxyphenethyl alcohol 3-O-β-D-glucopyranoside and cichoriin,respectively. CONCLUSION All compounds are isolated from Trollius for the first time,of which compound Ⅰ is a new natural product. |
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| Keywords: | Trollius ledebouri Reichb')" href=" #" > Trollius ledebouri Reichb Ranunculaceae 2-(3 O-β-D-glucopyranoside')" href=" #" >4-dihydroxyphenyl-2-hydroxyethyl alcohol-O-β-D-glucopyranoside chemical components |
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