阴道SIgA检测与阴道炎感染病原体类型的相关性及临床意义

目的 探讨体液免疫应答与阴道炎感染病原体类型的关系及临床意义。方法 198例已婚妇女取阴道分泌物(SIgA)采用双抗体-PEG法测定,同时用涂片及细菌培养检测病原菌。结果 滴虫阳性、细菌性阴道病及混合感染患者阴道分泌物SIgA明显高于病原体检测阴性及念珠菌阳性(P<0.01),但3者间无差异;念珠菌阳性患者阴道分泌物SIgA明显低于病原体检测阴性者(P<0.01);与滴虫阳性、细菌性阴道病及混合感染患者之间有显著差异(P<0.01)。结论 SIgA对阴道黏膜具有重要的保护作用,可作为鉴别念珠菌性阴道炎的辅助诊断方法。

Relativity and Clinical Significance Between the Vaginal SIgA and the Infection Pathogenic Type in Vaginitis

OBJECTIVE To probe the relationship and clinical significance between the responsion of body fluid immunity and the infection pathogenic type in vaginitis. METHODS Using PEG, the vaginal SIgA was detected in 198 cases of signora, and pathogenic bacteria was detected by the way of smear and germiculture. RESULTS The vaginal SIgA of trichomonal vaginitis, bacterial vaginosis and mixed infection was obviously higher than that of feminine pathogenic bacteria ( P <0. 01), but there was no difference among three groups. The vaginal SIgA of candidal vaginitis was obviously lower than that of feminine pathogenic bacteria, trichomonal vaginitis, bacterial vaginosis and mixed in-fection(P <0. 01) . CONCLUSIONS SIgA has the important protection function to the vaginal mucous membrane and can be used as to discriminate and lend support to the diagnosis method to candidal vaginitis.