Acute renal failure in children: prognostic features after treatment with acute dialysis |
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| Authors: | G. Offner J. Brodehl R. Galaske T. Rutt |
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| Affiliation: | (1) Dept. Paediatric Nephrology and Metabolic Diseases, Medical School of Hannover, Children's Hospital, D-3000 Hannover, Germany |
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| Abstract: | A 12-year review (1972–1983) is presented of 76 children who were dialysed because of acute renal failure. The causes of acute renal failure were mainly the haemolyticuraemic syndrome (53%), trauma (16%) and operation (13%).Fifty-eight children (76%) survived, 18 children (24%) died. Fifty-two children, the majority suffering from haemolytic-uraemic syndrome, regained complete or partial renal function after a period of dialysis lasting between 1 and 57 days. One to 7.7 years after dialysis, clearance studies with inulin (CIn), p-aminohippuric acid (CPAH) and phosphate (Tp/CIn) for staging renal function were carried out. The results of this investigation show a significant inverse correlation between the glomerular function regained and the duration of intermittent dialysis.Abbreviations CIn clearance of inulin - CPAH clearance of p-aminohippuric acid - FF filtration fraction - Tp/CIn fractional phosphate reabsorption - HUS haemolytic-uraemic syndrome - ARF acute renal failure - SCR serum creatinine - GFR glomerular filtration rate - CRF chronic renal failure - a.t. antihypertensive treatment |
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| Keywords: | Acute renal failure in childhood Haemolytic-uraemic syndrome |
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