| 外源性3’,5’环腺苷酸对人肺腺癌细胞系及裸小鼠移植瘤的作用 |
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| 引用本文： | 张道荣,赫明昌,王万忠,刘静敏,张丽宏,姜涛. 外源性3’,5’环腺苷酸对人肺腺癌细胞系及裸小鼠移植瘤的作用[J]. 中国医科大学学报, 1991, 0(3) |
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| 作者姓名： | 张道荣 赫明昌 王万忠 刘静敏 张丽宏 姜涛 |
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| 作者单位： | 中国医科大学基础医学部病理解剖学教研室(张道荣，赫明昌，王万忠，刘静敏，张丽宏)，中国医科大学基础医学部病理解剖学教研室(姜涛) |
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| 摘 要： | 用外源性3′,5′环腺苷酸(3′,5′cAMP)对人肺腺癌细胞系的连续作用,观察到癌细胞的增殖受到明显抑制,同时观察到在3′,5′cAMP作用下的癌细胞在裸小鼠体内移植瘤生长受到一定的抑制,但7周抑制作用基本消失。
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| 关 键 词： | 3′ 5′环腺苷酸 人肺腺癌细胞系AGZY-83a:裸小鼠移植瘤 |
EFFECT OF EXOGENOUS cAMP ON HUMAN LUNG GLANDULAR CARCINOMA AGZY-83a CELLS AND HETEROTRANSPLANTED TUMOR IN MICE |
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| Zhang Daorong,et al Dept. of Pathology. EFFECT OF EXOGENOUS cAMP ON HUMAN LUNG GLANDULAR CARCINOMA AGZY-83a CELLS AND HETEROTRANSPLANTED TUMOR IN MICE[J]. Journal of China Medical University, 1991, 0(3) |
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| Authors: | Zhang Daorong et al Dept. of Pathology |
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| Abstract: | The experiment was carried out on cultured human lung glandular carcinoma(AGZY-83a cell line) by continuous effect of exogenous cAMP. We observedthat cAMP not only inhibited the growth of these AGZY-83a cells, but alsoinhibited the growth of heterotransplanted tumor in nude mice. The inhibitedeffect disappeared about 50 days after administration of cAMP. |
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| Keywords: | 3' 5'adenosine monophosphate heterotransplated human lung glandular carcinoma AGZY-83a cell line tumor in nude mice |
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