| 梭曼及其代谢产物的分析方法及应用 |
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| 引用本文： | 李劲彤,阮金秀. 梭曼及其代谢产物的分析方法及应用[J]. 军事医学科学院院刊, 2000, 24(3): 229-231 |
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| 作者姓名： | 李劲彤 阮金秀 |
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| 作者单位： | 军事医学科学院毒物药物研究所,北京,100850 |
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| 摘 要： | 综述了梭曼及其代谢产物分析方法以及它们在梭曼的毒理学、毒动力学及毒检中的应用，其中，手性毛细管柱气相色谱法或气质联用仪是实现俊曼四个异构体分离测定的较好手段；对梭生谢产物的分析测定可以作为监测俊曼中毒的有力工具。
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| 关 键 词： | 梭曼 代谢产物 毒代动力学 毒理学 GC 测定 |
Analytic methods for soman and its metabolites and their application |
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| LI Jin-tong,RUAN Jin-xiu. Analytic methods for soman and its metabolites and their application[J]. Bulletin of the Academy of Military Medical Sciences, 2000, 24(3): 229-231 |
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| Authors: | LI Jin-tong RUAN Jin-xiu |
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| Abstract: | Analytic methods for soman and its metabolites and their application to toxicology, toxicokinetics and detection of poisons are reviewed. Among these methods, capillary gas chromatography and gas chromatography-mass spectrometry can distinguish the four stereoisomers of soman well. Meanwhile, determination of acid metabolites of soman can serve as a potent chemical marker for monitoring soman exposure. [ |
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| Keywords: | soman metabolite toxicokinetics |
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