| 青娥丸加减治疗绝经后妇女冠心病心绞痛患者临床研究 |
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| 引用本文： | 杨丁友,段学忠,张蕴慧,周次清.青娥丸加减治疗绝经后妇女冠心病心绞痛患者临床研究[J].中国自然医学杂志,2001,3(1):14-17. |
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| 作者姓名： | 杨丁友 段学忠 张蕴慧 周次清 |
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| 作者单位： | 1. 250031,济南,济南军区总医院
2. 山东中医药大学附属医院 |
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| 摘 要： | 目的：探讨青娥丸加减方对绝经后冠心病心绞痛患的临床疗效及血清雌激素（E2）、一氧化氮（NO）等水平的影响。方法：选100例绝经后冠心病心绞痛患，随机分为治疗组及对照组，均予抗心绞痛药物的同时，治疗组加服青娥丸加减方，对照组予尼尔雌醇替代治疗，检测用药前后心绞痛发作次数及E2、NO等水平的变径。结果：治疗组用药前后临床疗效及E2、NO等指标改善显（P＜0．01），且提高NO水平优于对照组（P＜0．01）。结论：青娥丸加减方可增加冠状动脉血流量以抗心绞痛，并有雌激素样作用。
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| 关 键 词： | 青娥丸 治疗 绝经后妇女 冠心病 心绞痛 雌激素 一氧化氮 中药 |
| 修稿时间： | 2000年10月18 |
Clinical studies on Qingewan jiajianfang (QEWJJF) in treating post-menopausal women with angina |
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| YANG Ding-you,DUAN Xue-zhong,ZHANG Yun - hui,el al.Clinical studies on Qingewan jiajianfang (QEWJJF) in treating post-menopausal women with angina[J].Chinese Journal of Natural Medicine,2001,3(1):14-17. |
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| Authors: | YANG Ding-you DUAN Xue-zhong ZHANG Yun - hui el al |
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| Institution: | YANG Ding-you,DUAN Xue-zhong,ZHANG Yun - hui,el al. General Hospital of Jinan Military' Area,Jinan 250031,Cina |
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| Abstract: | Objective To study the effect of Qingewanjiajianfang on post-menopausal women with angina and its influence on serum estradiol (E2) and nitric oxide (NO) levels. Methocb One hundred patients of post-menopausal women with angina were divided randomly into two groups,The treatment group was treated with QEWJJF and control group with estrogen besides conventional drugs. The changes of angina, NO and E2 levels were observed before and after the treatment.Results After treatment, the NO and E2 in the treatment group were improved obviously (P<0.01) compared with that in control group.Conclusion QEWJJF can act against myocar-dial ischemia and angina effectively. |
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| Keywords: | Coronary disease Post-menopausal women Estrogen Nitric oxide |
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